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COPD_&_CAD_data

dataset
posted on 15.06.2022, 11:28 authored by Mohani-Preet DhillonMohani-Preet Dhillon, Cathy SpillingCathy Spilling, Daniel Burrage, Sachelle Ruickbie, Thomas Barrick, Paul Jones, Emma Baker

The dataset comprises demographics and a range of biomedical variables from a cohort of 100 patients (53 patients with a primary diagnosis of Chronic Obstructive Pulmonary Disease (COPD), 24 with a primary diagnosis of coronary artery disease (CAD) and 23 with both COPD and CAD. Patients were recruited from respiratory and cardiology departments at St George's Hospital NHS Foundation Trust between December 2015 and October 2017. Variables include a range of markers of respiratory function, systemic inflammation, cognitive function and structural white matter damage (from brain magnetic resonance imaging).

Ethical approval was granted by the national research ethics committee London - Dulwich (16/LO/0547) and East Midlands - Leicester South Research Ethics Committee (15/EM/0425). All patients provided informed written consent.

Raw data is provided on Sheet 1 of the Excel file. A number of variables had a non-Guassian distribution. These variables were transformed using log10 or square root transformations.

Funding

Novel vascular complications of chronic obstructive pulmonary disease: a prospective clinical and imaging study to evaluate the effect of acute exacerbations of chronic obstructive pulmonary disease on cerebral small vessel disease and microvasculature.

NIHR Trainees Coordinating Centre

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