A randomised Phase II trial to evaluate the toxicity of high-dose rifampicin to treat pulmonary tuberculosis (Rifatox)
dataset
posted on 2024-11-25, 11:26 authored by Amina JindaniAmina Jindani, G. Borgulya, I. Westermann de Patiño, T. Gonzales, R.A. de Fernandes, B Shrestha, Atwine, D., M. Bonnet, M. Burgos, F. Dubash, N. Patel, A. M. Checkley, T.S. Harrison, D MitchisonA daily dose of 20 mg/kg RMP for 4 months appears to be safe and well-tolerated.
Although the treatment groups are relatively small, these encouraging results suggest that a daily dose of 20 mg/kg RMP for 4 months is safe enough to be taken forward to larger Phase III trials.
Funding
St. George's, University of London
History
Research Institute
- Infection and Immunity
